Gout
Gout(Presents as a Swelling in one joint, most commonly Great Toe)It is a metabolic disorder characterized by recurrent attacks of acute inflammatory arthritis�a red, tender, hot, swollen joint.
Colchicine is very effective for pain relief in acute gout but not used frequently due to its side effects.These drugs decrease in blood uric acid levels by increasing excretion of uric acid in urine (Probenecid and Sulfinpyrazone) or reducing production of uric acid (Allopurinol) inside the body.It is important to remember that while taking Probenecid or Sulfinpyrazone one should take plenty of water.